Prednisone vs Upadacitinib

## Prednisone vs Upadacitinib: Overview

This comparison examines the pharmacological differences between **Prednisone** and **Upadacitinib**.

## Mechanism of Action

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

**Upadacitinib**: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

## Pharmacokinetics

**Half-life**: Prednisone — 2-3 hours; Upadacitinib — 9-14 hours.

## Chemical Properties

**Molecular Formula**: Prednisone — C21H26O5; Upadacitinib — C17H19F3N6O.

**Molecular Weight**: Prednisone — 358.4280 g/mol; Upadacitinib — 380.3700 g/mol.

**Type**: Prednisone — Small molecule; Upadacitinib — Small molecule.