Abacavir

CHEMBL1380 Phase 4 Approuvé Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
286.3 g/mol
LogP
0.9
Phase
4

An antiviral medication used to treat HIV infection by blocking the virus's ability to copy its genetic material inside human cells. It is typically taken as part of a combination HIV regimen and helps keep the virus at undetectable levels in the blood. Before starting this medicine, a genetic test is recommended because a small number of people carry a gene variant that can cause a serious allergic reaction.

Masse moléculaire

286,3300 g/mol

LogP

0,90

TPSA

102,00 Ų

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

Nc1nc(NC2CC2)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1

InChI

InChI=1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1

Molecular Formula

C14H18N6O

HBD / HBA

3 / 6

Liaisons Rotatives

4

Atomes Lourds

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An antiviral medication used to treat HIV infection by blocking the virus's ability to copy its genetic material inside human cells. It is typically taken as part of a combination HIV regimen and helps keep the virus at undetectable levels in the blood. Before starting this medicine, a genetic test is recommended because a small number of people carry a gene variant that can cause a serious allergic reaction.

Yes, Abacavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1380. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 441300. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.