Acebutolol Hydrochloride

CHEMBL1200813 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

372.9 g/mol

LogP

—

Phase

4

The hydrochloride salt form of acebutolol, a cardioselective beta-blocker used for high blood pressure and heart rhythm disturbances. It has the same heart-slowing and blood pressure-lowering properties as acebutolol and is taken once or twice daily. Patients with asthma or chronic obstructive lung disease should use it with caution, as beta-blockers can narrow the airways.

Masse moléculaire

372,9000 g/mol

TPSA

87,70 Å²

Aires thérapeutiques

Hypertension Heart Failure Atrial Fibrillation Cardiovascular Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C(C)=O)c1.Cl

InChI

InChI=1S/C18H28N2O4.ClH/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3;/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23);1H

Molecular Formula

C18H29ClN2O4

HBD / HBA

4 / 5

Liaisons Rotatives

10

Atomes Lourds

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

The hydrochloride salt form of acebutolol, a cardioselective beta-blocker used for high blood pressure and heart rhythm disturbances. It has the same heart-slowing and blood pressure-lowering properties as acebutolol and is taken once or twice daily. Patients with asthma or chronic obstructive lung disease should use it with caution, as beta-blockers can narrow the airways.

Yes, Acebutolol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200813. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 441307. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C18H29ClN2O4
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.