Amitriptyline Hydrochloride

CHEMBL1200964 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

313.9 g/mol

LogP

—

Phase

4

The hydrochloride salt form of amitriptyline, working identically to the parent compound by blocking reuptake of serotonin and norepinephrine to elevate mood and relieve certain pain conditions. It comes in tablet form and is among the most studied tricyclic antidepressants available.

Masse moléculaire

313,9000 g/mol

TPSA

3,20 Å²

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Parkinson's Disease Epilepsy Migraine Schizophrenia Generalized Anxiety Disorder Insomnia Gastroesophageal Reflux Disease Inflammatory Bowel Disease Multiple Sclerosis Stroke Lymphoma Major Depressive Disorder Breast Cancer Chronic Pain HIV/AIDS Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

CN(C)CCC=C1c2ccccc2CCc2ccccc21.Cl

InChI

InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

Molecular Formula

C20H24ClN

HBD / HBA

1 / 1

Liaisons Rotatives

3

Atomes Lourds

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

The hydrochloride salt form of amitriptyline, working identically to the parent compound by blocking reuptake of serotonin and norepinephrine to elevate mood and relieve certain pain conditions. It comes in tablet form and is among the most studied tricyclic antidepressants available.

Yes, Amitriptyline Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200964. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 11065. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C20H24ClN
Synonymes: 3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.