Amodiaquine

CHEMBL682 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

355.9 g/mol

LogP

2.6

Phase

4

An antimalarial drug that interferes with the parasite's ability to process a toxic byproduct of hemoglobin digestion, leading to the parasite's death. It is sometimes used in combination therapies for malaria and has been studied for activity against HIV.

Masse moléculaire

355,9000 g/mol

LogP

2,60

TPSA

48,40 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Malaria HIV/AIDS

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O

InChI

InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)

Molecular Formula

C20H22ClN3O

HBD / HBA

2 / 4

Liaisons Rotatives

6

Atomes Lourds

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An antimalarial drug that interferes with the parasite's ability to process a toxic byproduct of hemoglobin digestion, leading to the parasite's death. It is sometimes used in combination therapies for malaria and has been studied for activity against HIV.

Yes, Amodiaquine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL682. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2165. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C20H22ClN3O

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.