Apraclonidine

CHEMBL647 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

245.1 g/mol

LogP

1.3

Phase

4

An alpha-2 adrenergic agonist used as eye drops to lower intraocular pressure in glaucoma by reducing the production of aqueous humor inside the eye. It is particularly useful for controlling pressure spikes following laser eye procedures.

Masse moléculaire

245,1100 g/mol

LogP

1,30

TPSA

62,40 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Glaucoma Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

Nc1cc(Cl)c(N=C2NCCN2)c(Cl)c1

InChI

InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)

Molecular Formula

C9H10Cl2N4

HBD / HBA

3 / 2

Liaisons Rotatives

2

Atomes Lourds

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An alpha-2 adrenergic agonist used as eye drops to lower intraocular pressure in glaucoma by reducing the production of aqueous humor inside the eye. It is particularly useful for controlling pressure spikes following laser eye procedures.

Yes, Apraclonidine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL647. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2216. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C9H10Cl2N4
Synonymes: 3

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.