Atropine Sulfate
The sulfate salt form of atropine, the standard injectable and ophthalmic formulation that blocks muscarinic receptors to speed the heart rate in bradycardia, dilate the pupils for eye examinations, and dry airway secretions before surgery. It is also an antidote for organophosphate and nerve agent poisoning.
Masse moléculaire
676,8000 g/mol
TPSA
183,00 Ų
Aires thérapeutiques
Mécanisme d'action
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Structure 2D
Cite this structure
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SMILES
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2.O=S(=O)(O)O
InChI
InChI=1S/C17H23NO3.H2O4S/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4/h2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4)/t13-,14+,15+,16?;
Molecular Formula
C34H48N2O10S
HBD / HBA
4 / 12
Liaisons Rotatives
10
Atomes Lourds
47
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
The sulfate salt form of atropine, the standard injectable and ophthalmic formulation that blocks muscarinic receptors to speed the heart rate in bradycardia, dilate the pupils for eye examinations, and dry airway secretions before surgery. It is also an antidote for organophosphate and nerve agent poisoning.
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.
Yes, Atropine Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2146146. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60196398. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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