Azelaic Acid

CHEMBL1238 Phase 4 Approuvé Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
188.2 g/mol
LogP
1.6
Phase
4

A naturally occurring dicarboxylic acid with antibacterial and anti-inflammatory properties that reduces acne-causing bacteria on the skin and inhibits the production of abnormal pigment. It is useful for treating acne and rosacea.

Masse moléculaire

188,2200 g/mol

LogP

1,60

TPSA

74,60 Ų

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Mécanisme d'action

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Structure 2D

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SMILES

O=C(O)CCCCCCCC(=O)O

InChI

InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)

Molecular Formula

C9H16O4

HBD / HBA

2 / 4

Liaisons Rotatives

8

Atomes Lourds

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A naturally occurring dicarboxylic acid with antibacterial and anti-inflammatory properties that reduces acne-causing bacteria on the skin and inhibits the production of abnormal pigment. It is useful for treating acne and rosacea.

Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.

Yes, Azelaic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1238. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2266. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.