Azlocillin

CHEMBL1537 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

461.5 g/mol

LogP

0.1

Phase

4

A broad-spectrum acylaminopenicillin antibiotic with enhanced activity against Pseudomonas aeruginosa that disrupts bacterial cell wall synthesis. It has largely been replaced by other antipseudomonal agents.

Masse moléculaire

461,5000 g/mol

LogP

0,10

TPSA

173,00 Å²

Règle des 5 de Lipinski

Conforme

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c3ccccc3)C(=O)N2[C@H]1C(=O)O

InChI

InChI=1S/C20H23N5O6S/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29)/t11-,12-,13+,16-/m1/s1

Molecular Formula

C20H23N5O6S

HBD / HBA

4 / 7

Liaisons Rotatives

5

Atomes Lourds

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A broad-spectrum acylaminopenicillin antibiotic with enhanced activity against Pseudomonas aeruginosa that disrupts bacterial cell wall synthesis. It has largely been replaced by other antipseudomonal agents.

Yes, Azlocillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1537. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6479523. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C20H23N5O6S

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.