Aztreonam

CHEMBL158 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

435.4 g/mol

LogP

0.3

Phase

4

A monobactam antibiotic that targets only Gram-negative bacteria by binding to a specific penicillin-binding protein, disrupting cell wall synthesis. It is used in patients allergic to penicillin for treatment of serious Gram-negative infections.

Masse moléculaire

435,4000 g/mol

LogP

0,30

TPSA

238,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Infectious Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)c2csc(N)n2)C(=O)N1S(=O)(=O)O

InChI

InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

Molecular Formula

C13H17N5O8S2

HBD / HBA

4 / 12

Liaisons Rotatives

7

Atomes Lourds

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A monobactam antibiotic that targets only Gram-negative bacteria by binding to a specific penicillin-binding protein, disrupting cell wall synthesis. It is used in patients allergic to penicillin for treatment of serious Gram-negative infections.

Yes, Aztreonam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL158. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5742832. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C13H17N5O8S2
Synonymes: 3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.