Bordetella Pertussis Toxin
The inactivated toxin produced by Bordetella pertussis bacteria and included in acellular pertussis vaccines to induce protective immunity against whooping cough. The toxin plays a central role in the disease process, and antibodies against it are important for protection. Inactivation ensures it is safe for use in vaccines while retaining immunogenicity.
Aires thérapeutiques
Mécanisme d'action
Stimulates the adaptive immune system to produce antigen-specific antibodies and memory cells, providing protective immunity against subsequent exposure to the pathogen.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Stimulates the adaptive immune system to produce antigen-specific antibodies and memory cells, providing protective immunity against subsequent exposure to the pathogen.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
The inactivated toxin produced by Bordetella pertussis bacteria and included in acellular pertussis vaccines to induce protective immunity against whooping cough. The toxin plays a central role in the disease process, and antibodies against it are important for protection. Inactivation ensures it is safe for use in vaccines while retaining immunogenicity.
Stimulates the adaptive immune system to produce antigen-specific antibodies and memory cells, providing protective immunity against subsequent exposure to the pathogen.
Yes, Bordetella Pertussis Toxin is an approved drug. It has reached clinical phase 4. It is classified as a Vaccine component.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068349. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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