Ceftazidime Sodium
The sodium salt form of ceftazidime, prepared for intravenous or intramuscular injection to treat serious gram-negative infections. It shares the anti-Pseudomonal coverage of the parent drug and is commonly used in intensive care settings. When used in combination with avibactam, it extends coverage to carbapenem-resistant Enterobacteriaceae.
Masse moléculaire
568,6000 g/mol
TPSA
248,00 Ų
Aires thérapeutiques
Mécanisme d'action
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Structure 2D
Cite this structure
Embed this structure
SMILES
CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CS[C@H]12)c1csc(N)n1)C(=O)[O-].[Na+]
InChI
InChI=1S/C22H22N6O7S2.Na/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);/q;+1/p-1/b26-13-;/t14-,18-;/m1./s1
Molecular Formula
C22H21N6NaO7S2
HBD / HBA
2 / 12
Liaisons Rotatives
7
Atomes Lourds
38
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
The sodium salt form of ceftazidime, prepared for intravenous or intramuscular injection to treat serious gram-negative infections. It shares the anti-Pseudomonal coverage of the parent drug and is commonly used in intensive care settings. When used in combination with avibactam, it extends coverage to carbapenem-resistant Enterobacteriaceae.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Ceftazidime Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200768. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5488543. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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