Choline C-11

CHEMBL2095207 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

103.2 g/mol

LogP

-0.4

Phase

4

A radiotracer consisting of radiolabeled choline used in positron emission tomography (PET) imaging to detect recurrent prostate cancer. Cancer cells take up choline at increased rates as a substrate for membrane phospholipid synthesis. This allows detection of metastatic disease, particularly when conventional imaging is negative.

Masse moléculaire

103,1700 g/mol

LogP

-0,40

TPSA

20,20 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

C[N+](C)([11CH3])CCO.[Cl-]

InChI

InChI=1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1/i1-1;

Molecular Formula

C5H14NO+

HBD / HBA

1 / 1

Liaisons Rotatives

2

Atomes Lourds

7

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A radiotracer consisting of radiolabeled choline used in positron emission tomography (PET) imaging to detect recurrent prostate cancer. Cancer cells take up choline at increased rates as a substrate for membrane phospholipid synthesis. This allows detection of metastatic disease, particularly when conventional imaging is negative.

Yes, Choline C-11 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2095207. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 449688. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C5H14NO+
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.