Clofazimine

CHEMBL1292 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

473.4 g/mol

LogP

7.1

Phase

4

A fat-soluble riminophenazine dye antibiotic with anti-inflammatory properties used primarily to treat leprosy and drug-resistant tuberculosis. It accumulates in fatty tissues and skin, giving patients a reddish-brown discoloration during treatment.

Masse moléculaire

473,4000 g/mol

LogP

7,10

TPSA

40,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Multiple Sclerosis HIV/AIDS Tuberculosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CC(C)/N=c1\cc2n(-c3ccc(Cl)cc3)c3ccccc3nc-2cc1Nc1ccc(Cl)cc1

InChI

InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3/b30-24+

Molecular Formula

C27H22Cl2N4

HBD / HBA

1 / 4

Liaisons Rotatives

4

Atomes Lourds

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A fat-soluble riminophenazine dye antibiotic with anti-inflammatory properties used primarily to treat leprosy and drug-resistant tuberculosis. It accumulates in fatty tissues and skin, giving patients a reddish-brown discoloration during treatment.

Yes, Clofazimine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1292. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2794. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C27H22Cl2N4

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.