Diethylstilbestrol

CHEMBL411 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

268.3 g/mol

LogP

5.1

Phase

4

A synthetic nonsteroidal estrogen that was widely prescribed from the 1940s to 1970s to prevent miscarriage, though it was later found to be ineffective for this purpose. Its use in pregnant women led to serious reproductive tract abnormalities and cancers in their children, particularly clear cell carcinoma of the vagina in daughters. It is now used in limited circumstances for prostate cancer treatment.

Masse moléculaire

268,3000 g/mol

LogP

5,10

TPSA

40,50 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Migraine Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

CC/C(=C(/CC)c1ccc(O)cc1)c1ccc(O)cc1

InChI

InChI=1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+

Molecular Formula

C18H20O2

HBD / HBA

2 / 2

Liaisons Rotatives

4

Atomes Lourds

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A synthetic nonsteroidal estrogen that was widely prescribed from the 1940s to 1970s to prevent miscarriage, though it was later found to be ineffective for this purpose. Its use in pregnant women led to serious reproductive tract abnormalities and cancers in their children, particularly clear cell carcinoma of the vagina in daughters. It is now used in limited circumstances for prostate cancer treatment.

Yes, Diethylstilbestrol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL411. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 448537. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C18H20O2
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.