Disulfiram

CHEMBL964 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

296.5 g/mol

LogP

3.9

Phase

4

A medication used as a deterrent in the treatment of alcoholism by causing an extremely unpleasant reaction (flushing, nausea, vomiting, palpitations, and hypotension) when alcohol is consumed while taking it. It works by inhibiting aldehyde dehydrogenase, causing accumulation of toxic acetaldehyde when alcohol is metabolized. It requires patient motivation and should only be used in fully abstinent patients who understand the consequences of drinking.

Masse moléculaire

296,5000 g/mol

LogP

3,90

TPSA

121,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Age-Related Macular Degeneration Non-Small Cell Lung Cancer Generalized Anxiety Disorder Melanoma Obesity Breast Cancer HIV/AIDS Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

CCN(CC)C(=S)SSC(=S)N(CC)CC

InChI

InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3

Molecular Formula

C10H20N2S4

HBD / HBA

- / 4

Liaisons Rotatives

7

Atomes Lourds

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A medication used as a deterrent in the treatment of alcoholism by causing an extremely unpleasant reaction (flushing, nausea, vomiting, palpitations, and hypotension) when alcohol is consumed while taking it. It works by inhibiting aldehyde dehydrogenase, causing accumulation of toxic acetaldehyde when alcohol is metabolized. It requires patient motivation and should only be used in fully abstinent patients who understand the consequences of drinking.

Yes, Disulfiram is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL964. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3117. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C10H20N2S4
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.