Doxazosin

CHEMBL707 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

451.5 g/mol

LogP

2.5

Phase

4

An alpha-blocker used to treat high blood pressure and to relieve urinary symptoms associated with an enlarged prostate (BPH). It works by relaxing muscles in blood vessels and the prostate.

Masse moléculaire

451,5000 g/mol

LogP

2,50

TPSA

112,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Benign Prostatic Hyperplasia Cardiovascular Disease Generalized Anxiety Disorder Chronic Kidney Disease Stroke Hypertension Heart Failure Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)CC3)nc(N)c2cc1OC

InChI

InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)

Molecular Formula

C23H25N5O5

HBD / HBA

1 / 9

Liaisons Rotatives

4

Atomes Lourds

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An alpha-blocker used to treat high blood pressure and to relieve urinary symptoms associated with an enlarged prostate (BPH). It works by relaxing muscles in blood vessels and the prostate.

Yes, Doxazosin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL707. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3157. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C23H25N5O5
Synonymes: 3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.