Entecavir

CHEMBL5314362 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

277.3 g/mol

LogP

-1.3

Phase

4

This antiviral medication blocks the hepatitis B virus from copying its genetic material inside liver cells, reducing the amount of virus in the body. It is used for the long-term treatment of chronic hepatitis B infection.

Masse moléculaire

277,2800 g/mol

LogP

-1,30

TPSA

126,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Cardiovascular Disease Respiratory Disease Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Lymphoma Hypertension Hepatitis C Tuberculosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

C=C1[C@H](CO)[C@@H](O)C[C@@H]1n1cnc2c(=O)[nH]c(N)nc21.O

InChI

InChI=1S/C12H15N5O3.H2O/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20;/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20);1H2/t6-,7-,8-;/m0./s1

Molecular Formula

C12H15N5O3

HBD / HBA

4 / 5

Liaisons Rotatives

2

Atomes Lourds

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This antiviral medication blocks the hepatitis B virus from copying its genetic material inside liver cells, reducing the amount of virus in the body. It is used for the long-term treatment of chronic hepatitis B infection.

Yes, Entecavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5314362. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135398508. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C12H15N5O3
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.