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Esomeprazole

CHEMBL1201320 Phase 4 Approuvé Small molecule
Half-Life
1-1.5 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
345.4 g/mol
LogP
2.2
Phase
4

This proton pump inhibitor reduces stomach acid production by blocking the enzyme in the stomach lining that secretes acid. It is used to treat acid reflux, stomach ulcers, and conditions caused by too much stomach acid.

Masse moléculaire

345,4170 g/mol

LogP

2,20

TPSA

96,30 Ų

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Immunology Epilepsy Schizophrenia Generalized Anxiety Disorder Gastroesophageal Reflux Disease Psoriasis Multiple Sclerosis Non-Alcoholic Fatty Liver Disease Deep Vein Thrombosis / Pulmonary Embolism Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer

Classes de médicaments

A — A - Alimentary Tract and Metabolism

Mécanisme d'action

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

Pharmacokinetics (PK)

Half-Life 1-1.5 hours

Pharmacodynamics (PD)

Mécanisme

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1ccc2[nH]c([S@@+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1

                

                

                
                

                    
InChI

                    
InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C17H19N3O3S

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
Liaisons Rotatives

                        
5

                    

                    
                    
                    

                        
Atomes Lourds

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
This proton pump inhibitor reduces stomach acid production by blocking the enzyme in the stomach lining that secretes acid. It is used to treat acid reflux, stomach ulcers, and conditions caused by too much stomach acid.

                        

                    

                    

                    

                    
                    

                        
                        

                            
S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Esomeprazole: Half-life: 1-1.5 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Esomeprazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Metformin
                            Small molecule
                        
                        
                        
                            Omeprazole
                            Small molecule
                        
                        
                        
                            Pantoprazole
                            Small molecule
                        
                        
                        
                            Lansoprazole
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201320.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9568614.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.