Estradiol

CHEMBL135 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

272.4 g/mol

LogP

4.0

Phase

4

This form of the primary female sex hormone estrogen is used in hormone replacement therapy to relieve menopausal symptoms such as hot flashes and vaginal dryness. It also helps protect against bone loss after menopause.

Masse moléculaire

272,4000 g/mol

LogP

4,00

TPSA

40,50 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Insomnia Melanoma Psoriasis Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Hypertension Breast Cancer Atopic Dermatitis Chronic Pain HIV/AIDS Hepatitis C Tuberculosis Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O

InChI

InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

Molecular Formula

C18H24O2

HBD / HBA

2 / 2

Liaisons Rotatives

0

Atomes Lourds

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This form of the primary female sex hormone estrogen is used in hormone replacement therapy to relieve menopausal symptoms such as hot flashes and vaginal dryness. It also helps protect against bone loss after menopause.

Yes, Estradiol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL135. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5757. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C18H24O2
Synonymes: 308

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.