Estrone

CHEMBL1405 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

270.4 g/mol

LogP

3.1

Phase

4

This naturally occurring estrogen is the predominant estrogen in the body after menopause and is available for use in hormone replacement therapy. It helps relieve menopausal symptoms including vaginal dryness and hot flashes.

Masse moléculaire

270,4000 g/mol

LogP

3,10

TPSA

37,30 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Endometriosis Migraine Bipolar Disorder Generalized Anxiety Disorder Psoriasis Systemic Lupus Erythematosus Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Breast Cancer Atopic Dermatitis HIV/AIDS Hepatitis C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O

InChI

InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

Molecular Formula

C18H22O2

HBD / HBA

1 / 2

Liaisons Rotatives

0

Atomes Lourds

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This naturally occurring estrogen is the predominant estrogen in the body after menopause and is available for use in hormone replacement therapy. It helps relieve menopausal symptoms including vaginal dryness and hot flashes.

Yes, Estrone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1405. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5870. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C18H22O2
Synonymes: 5

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.