Etretinate

CHEMBL464 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

354.5 g/mol

LogP

6.8

Phase

4

This retinoid medication normalizes the growth and shedding of skin cells and was used to treat severe, treatment-resistant psoriasis. It has been withdrawn from most markets due to its long persistence in the body and severe risk of birth defects.

Masse moléculaire

354,5000 g/mol

LogP

6,80

TPSA

35,50 Å²

Règle des 5 de Lipinski

Conforme

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCOC(=O)/C=C(C)/C=C/C=C(C)/C=C/c1c(C)cc(OC)c(C)c1C

InChI

InChI=1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+

Molecular Formula

C23H30O3

HBD / HBA

- / 3

Liaisons Rotatives

8

Atomes Lourds

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This retinoid medication normalizes the growth and shedding of skin cells and was used to treat severe, treatment-resistant psoriasis. It has been withdrawn from most markets due to its long persistence in the body and severe risk of birth defects.

Yes, Etretinate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL464. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5282375. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C23H30O3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.