Floxuridine

CHEMBL917 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

246.2 g/mol

LogP

-1.2

Phase

4

This chemotherapy drug is converted in the body to compounds that disrupt DNA and RNA synthesis in rapidly dividing cancer cells. It is infused directly into the artery supplying the liver to treat cancer that has spread from the colon to the liver.

Masse moléculaire

246,1900 g/mol

LogP

-1,20

TPSA

99,10 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Non-Alcoholic Fatty Liver Disease Breast Cancer Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F

InChI

InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

Molecular Formula

C9H11FN2O5

HBD / HBA

3 / 6

Liaisons Rotatives

2

Atomes Lourds

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This chemotherapy drug is converted in the body to compounds that disrupt DNA and RNA synthesis in rapidly dividing cancer cells. It is infused directly into the artery supplying the liver to treat cancer that has spread from the colon to the liver.

Yes, Floxuridine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL917. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5790. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C9H11FN2O5

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.