Flunisolide
This inhaled corticosteroid reduces airway inflammation in asthma by suppressing the immune response in the bronchial passages. Used as a daily preventive controller medication, it does not provide immediate relief during an acute asthma attack.
Masse moléculaire
434,5000 g/mol
LogP
2,50
TPSA
93,10 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Mécanisme d'action
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Structure 2D
Cite this structure
Embed this structure
SMILES
CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
InChI
InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
Molecular Formula
C24H31FO6
HBD / HBA
2 / 7
Liaisons Rotatives
2
Atomes Lourds
31
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
This inhaled corticosteroid reduces airway inflammation in asthma by suppressing the immune response in the bronchial passages. Used as a daily preventive controller medication, it does not provide immediate relief during an acute asthma attack.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Flunisolide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1512. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 82153. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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