Ibutilide Fumarate

CHEMBL2355456 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

885.2 g/mol

LogP

—

Phase

4

This fumarate salt of ibutilide is the intravenous formulation used in hospitals to convert acute-onset atrial fibrillation or flutter to normal heart rhythm. It acts by prolonging the cardiac repolarization phase, which helps restore synchronized electrical activity. Continuous ECG monitoring is required during and after infusion due to proarrhythmic risk.

Masse moléculaire

885,2000 g/mol

TPSA

231,00 Å²

Aires thérapeutiques

Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.O=C(O)/C=C/C(=O)O

InChI

InChI=1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

Molecular Formula

C44H76N4O10S2

HBD / HBA

6 / 14

Liaisons Rotatives

30

Atomes Lourds

60

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This fumarate salt of ibutilide is the intravenous formulation used in hospitals to convert acute-onset atrial fibrillation or flutter to normal heart rhythm. It acts by prolonging the cardiac repolarization phase, which helps restore synchronized electrical activity. Continuous ECG monitoring is required during and after infusion due to proarrhythmic risk.

Yes, Ibutilide Fumarate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2355456. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5281065. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C44H76N4O10S2
Synonymes: 1

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.