Ioflupane I 123
A radioactive imaging agent used in SPECT brain scans to help diagnose Parkinson's disease and related movement disorders. It attaches to dopamine transporters in the brain, allowing doctors to assess dopamine activity.
Masse moléculaire
427,3000 g/mol
LogP
4,00
TPSA
29,50 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
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SMILES
COC(=O)[C@H]1[C@@H](c2ccc([123I])cc2)C[C@@H]2CC[C@H]1N2CCCF
InChI
InChI=1S/C18H23FINO2/c1-23-18(22)17-15(12-3-5-13(20)6-4-12)11-14-7-8-16(17)21(14)10-2-9-19/h3-6,14-17H,2,7-11H2,1H3/t14-,15+,16+,17-/m0/s1/i20-4
Molecular Formula
C18H23FINO2
HBD / HBA
- / 4
Liaisons Rotatives
6
Atomes Lourds
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
A radioactive imaging agent used in SPECT brain scans to help diagnose Parkinson's disease and related movement disorders. It attaches to dopamine transporters in the brain, allowing doctors to assess dopamine activity.
Yes, Ioflupane I 123 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989517. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3086674. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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