Iothalamate Sodium I 125

CHEMBL2106318 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

629.9 g/mol

LogP

—

Phase

4

A radioactive form of iothalamate labeled with iodine-125, used as a reference standard to accurately measure the glomerular filtration rate (GFR) and assess kidney function. It is given by injection and its clearance from the blood reflects how efficiently the kidneys are filtering.

Masse moléculaire

629,9000 g/mol

TPSA

98,30 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CNC(=O)c1c(I)c(NC(C)=O)c([125I])c(C(=O)[O-])c1[125I].[Na+]

InChI

InChI=1S/C11H9I3N2O4.Na/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20;/h1-2H3,(H,15,18)(H,16,17)(H,19,20);/q;+1/p-1/i12-2,14-2;

Molecular Formula

C11H8I3N2NaO4

HBD / HBA

2 / 4

Liaisons Rotatives

3

Atomes Lourds

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A radioactive form of iothalamate labeled with iodine-125, used as a reference standard to accurately measure the glomerular filtration rate (GFR) and assess kidney function. It is given by injection and its clearance from the blood reflects how efficiently the kidneys are filtering.

Yes, Iothalamate Sodium I 125 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2106318. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 23724931. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C11H8I3N2NaO4

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.