Iptacopan

CHEMBL4594448 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

422.5 g/mol

LogP

1.8

Phase

4

An oral complement factor B inhibitor for paroxysmal nocturnal hemoglobinuria.

Masse moléculaire

422,5000 g/mol

LogP

1,80

TPSA

74,80 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Age-Related Macular Degeneration Systemic Lupus Erythematosus

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1

InChI

InChI=1S/C25H30N2O4/c1-4-31-19-10-12-27(22(14-19)17-5-7-18(8-6-17)25(28)29)15-21-20-9-11-26-24(20)16(2)13-23(21)30-3/h5-9,11,13,19,22,26H,4,10,12,14-15H2,1-3H3,(H,28,29)/t19-,22-/m0/s1

Molecular Formula

C25H30N2O4

HBD / HBA

2 / 5

Liaisons Rotatives

7

Atomes Lourds

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An oral complement factor B inhibitor for paroxysmal nocturnal hemoglobinuria.

Yes, Iptacopan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594448. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 90467622. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C25H30N2O4
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.