Isoproterenol
This synthetic catecholamine acts as a non-selective beta-adrenergic agonist, stimulating both beta-1 receptors in the heart (increasing heart rate and contractility) and beta-2 receptors in the lungs (causing bronchodilation). It is used in emergency settings for heart block, bradycardia, and bronchospasm. Its cardiac-stimulating effects limit its use compared to more selective agents.
Masse moléculaire
211,2600 g/mol
LogP
-0,60
TPSA
72,70 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
Embed this structure
SMILES
CC(C)NCC(O)c1ccc(O)c(O)c1
InChI
InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
Molecular Formula
C11H17NO3
HBD / HBA
4 / 4
Liaisons Rotatives
4
Atomes Lourds
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
This synthetic catecholamine acts as a non-selective beta-adrenergic agonist, stimulating both beta-1 receptors in the heart (increasing heart rate and contractility) and beta-2 receptors in the lungs (causing bronchodilation). It is used in emergency settings for heart block, bradycardia, and bronchospasm. Its cardiac-stimulating effects limit its use compared to more selective agents.
Yes, Isoproterenol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL434. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3779. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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