Latanoprostene Bunod

CHEMBL2364612 Phase 4 Approuvé Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
507.6 g/mol
LogP
4.4
Phase
4

A nitric oxide-donating prostaglandin analog used to lower intraocular pressure in open-angle glaucoma and ocular hypertension. It works through a dual mechanism, enhancing both the conventional and uveoscleral fluid drainage pathways.

Masse moléculaire

507,6000 g/mol

LogP

4,40

TPSA

142,00 Ų

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Mécanisme d'action

Absorbs, reflects, or scatters ultraviolet radiation before it reaches the skin, protecting against UV-induced DNA damage and sunburn.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Absorbs, reflects, or scatters ultraviolet radiation before it reaches the skin, protecting against UV-induced DNA damage and sunburn.

Structure 2D

SVG PNG

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SMILES

O=C(CCC/C=C\C[C@@H]1[C@@H](CC[C@@H](O)CCc2ccccc2)[C@H](O)C[C@@H]1O)OCCCCO[N+](=O)[O-]

InChI

InChI=1S/C27H41NO8/c29-22(15-14-21-10-4-3-5-11-21)16-17-24-23(25(30)20-26(24)31)12-6-1-2-7-13-27(32)35-18-8-9-19-36-28(33)34/h1,3-6,10-11,22-26,29-31H,2,7-9,12-20H2/b6-1-/t22-,23+,24+,25-,26+/m0/s1

Molecular Formula

C27H41NO8

HBD / HBA

3 / 8

Liaisons Rotatives

18

Atomes Lourds

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A nitric oxide-donating prostaglandin analog used to lower intraocular pressure in open-angle glaucoma and ocular hypertension. It works through a dual mechanism, enhancing both the conventional and uveoscleral fluid drainage pathways.

Absorbs, reflects, or scatters ultraviolet radiation before it reaches the skin, protecting against UV-induced DNA damage and sunburn.

Yes, Latanoprostene Bunod is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2364612. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11156438. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.