Lenvatinib

CHEMBL1289601 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

426.9 g/mol

LogP

2.8

Phase

4

A multi-kinase inhibitor used to treat thyroid cancer, hepatocellular carcinoma, renal cell carcinoma, and endometrial cancer. It blocks multiple receptors involved in tumor blood vessel formation and cancer cell proliferation.

Masse moléculaire

426,9000 g/mol

LogP

2,80

TPSA

116,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Melanoma Lymphoma Hypertension Breast Cancer Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O

InChI

InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)

Molecular Formula

C21H19ClN4O4

HBD / HBA

3 / 5

Liaisons Rotatives

6

Atomes Lourds

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A multi-kinase inhibitor used to treat thyroid cancer, hepatocellular carcinoma, renal cell carcinoma, and endometrial cancer. It blocks multiple receptors involved in tumor blood vessel formation and cancer cell proliferation.

Yes, Lenvatinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1289601. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9823820. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C21H19ClN4O4
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.