Levomefolic Acid

CHEMBL1231574 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

459.5 g/mol

LogP

-0.5

Phase

4

The active methylated form of folate, also known as 5-methyltetrahydrofolate (5-MTHF), that does not require enzymatic conversion and is used directly in cellular methylation reactions. It supports brain health and is used in supplements for people with MTHFR gene variants.

Masse moléculaire

459,5000 g/mol

LogP

-0,50

TPSA

198,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Alzheimer's Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

CN1c2c([nH]c(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

InChI

InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1

Molecular Formula

C20H25N7O6

HBD / HBA

7 / 10

Liaisons Rotatives

9

Atomes Lourds

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

The active methylated form of folate, also known as 5-methyltetrahydrofolate (5-MTHF), that does not require enzymatic conversion and is used directly in cellular methylation reactions. It supports brain health and is used in supplements for people with MTHFR gene variants.

Yes, Levomefolic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1231574. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135398561. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Vous cherchez des informations accessibles aux patients ?

Levomefolic Acid sur PillFYI

Structure

Données Clés

Formule: C20H25N7O6
Synonymes: 3

Liens externes

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.