Melatonin
A naturally occurring hormone produced by the pineal gland that regulates the sleep-wake cycle, available as a supplement to treat insomnia, jet lag, and sleep disorders in shift workers and people with circadian rhythm disturbances. It is also being studied for potential roles in neurodegenerative disease management.
Masse moléculaire
232,2800 g/mol
LogP
0,80
TPSA
54,10 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
Embed this structure
SMILES
COc1ccc2[nH]cc(CCNC(C)=O)c2c1
InChI
InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
Molecular Formula
C13H16N2O2
HBD / HBA
2 / 2
Liaisons Rotatives
4
Atomes Lourds
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
A naturally occurring hormone produced by the pineal gland that regulates the sleep-wake cycle, available as a supplement to treat insomnia, jet lag, and sleep disorders in shift workers and people with circadian rhythm disturbances. It is also being studied for potential roles in neurodegenerative disease management.
Yes, Melatonin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL45. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 896. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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