Methacycline
A broad-spectrum tetracycline antibiotic used to treat a variety of bacterial infections including respiratory tract infections, skin infections, and certain sexually transmitted diseases. It works by stopping the growth of bacteria and is taken by mouth.
Masse moléculaire
442,4000 g/mol
LogP
0,30
TPSA
182,00 Ų
Règle des 5 de Lipinski
Conforme
Mécanisme d'action
Binds reversibly to the 30S ribosomal subunit, blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor (A) site. This inhibits bacterial protein synthesis in a bacteriostatic manner.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds reversibly to the 30S ribosomal subunit, blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor (A) site. This inhibits bacterial protein synthesis in a bacteriostatic manner.
Structure 2D
Cite this structure
Embed this structure
SMILES
C=C1c2cccc(O)c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12
InChI
InChI=1S/C22H22N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31)/t10-,14-,15+,17+,22+/m1/s1
Molecular Formula
C22H22N2O8
HBD / HBA
6 / 9
Liaisons Rotatives
2
Atomes Lourds
32
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
A broad-spectrum tetracycline antibiotic used to treat a variety of bacterial infections including respiratory tract infections, skin infections, and certain sexually transmitted diseases. It works by stopping the growth of bacteria and is taken by mouth.
Binds reversibly to the 30S ribosomal subunit, blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor (A) site. This inhibits bacterial protein synthesis in a bacteriostatic manner.
Yes, Methacycline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL249837. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 54675785. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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