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Midazolam Hydrochloride

CHEMBL1200420 Phase 4 Approuvé Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
362.2 g/mol
LogP
—
Phase
4

This is the hydrochloride salt form of midazolam used in injectable and intranasal formulations; see midazolam for full prescribing information.

Masse moléculaire

362,2000 g/mol

TPSA

30,20 Ų

Aires thérapeutiques

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Glaucoma Cardiovascular Disease Respiratory Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Melanoma Oncology Gastroesophageal Reflux Disease Inflammatory Bowel Disease Psoriasis Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Obesity Lymphoma Hypertension Major Depressive Disorder Breast Cancer Atopic Dermatitis Gout Chronic Pain Hepatitis C Tuberculosis Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Mécanisme d'action

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=NC2.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C18H13ClFN3.ClH/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13;/h2-9H,10H2,1H3;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H14Cl2FN3

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
Liaisons Rotatives

                        
1

                    

                    
                    
                    

                        
Atomes Lourds

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
This is the hydrochloride salt form of midazolam used in injectable and intranasal formulations; see midazolam for full prescribing information.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Ultra-short-acting benzodiazepine GABA-A receptor positive allosteric modulator.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Midazolam Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200420.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 43032.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.