Nepafenac

CHEMBL1021 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

254.3 g/mol

LogP

1.9

Phase

4

This non-steroidal anti-inflammatory eye drop is used to treat pain and inflammation after cataract surgery and to reduce the risk of swelling in the retina. It penetrates the eye tissues and converts to its active form to block inflammatory enzymes.

Masse moléculaire

254,2800 g/mol

LogP

1,90

TPSA

86,20 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Glaucoma Age-Related Macular Degeneration Pain Management Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N

InChI

InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)

Molecular Formula

C15H14N2O2

HBD / HBA

2 / 3

Liaisons Rotatives

4

Atomes Lourds

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This non-steroidal anti-inflammatory eye drop is used to treat pain and inflammation after cataract surgery and to reduce the risk of swelling in the retina. It penetrates the eye tissues and converts to its active form to block inflammatory enzymes.

Yes, Nepafenac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1021. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 151075. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C15H14N2O2
Synonymes: 2

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.