Nintedanib Esylate

CHEMBL3039504 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

649.8 g/mol

LogP

—

Phase

4

A esylate form of nintedanib with the same therapeutic properties. A targeted therapy that blocks multiple growth factor receptors involved in the development of new blood vessels that tumors need to grow.

Masse moléculaire

649,8000 g/mol

TPSA

164,00 Å²

Aires thérapeutiques

Infectious Disease Melanoma Ovarian Cancer Thyroid Cancer Respiratory Disease Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Lymphoma Breast Cancer Cardiovascular Disease Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

CCS(=O)(=O)O.COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1

InChI

InChI=1S/C31H33N5O4.C2H6O3S/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38;1-2-6(3,4)5/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38);2H2,1H3,(H,3,4,5)/b29-28-;

Molecular Formula

C33H39N5O7S

HBD / HBA

3 / 10

Liaisons Rotatives

9

Atomes Lourds

46

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A esylate form of nintedanib with the same therapeutic properties. A targeted therapy that blocks multiple growth factor receptors involved in the development of new blood vessels that tumors need to grow.

Yes, Nintedanib Esylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3039504. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135476717. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C33H39N5O7S

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.