Nitisinone

CHEMBL1337 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

329.2 g/mol

LogP

2.3

Phase

4

A medication used to treat hereditary tyrosinemia type 1 by blocking an enzyme in the tyrosine breakdown pathway.

Masse moléculaire

329,2300 g/mol

LogP

2,30

TPSA

97,00 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Cardiovascular Disease Respiratory Disease Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]

InChI

InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2

Molecular Formula

C14H10F3NO5

HBD / HBA

- / 8

Liaisons Rotatives

2

Atomes Lourds

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A medication used to treat hereditary tyrosinemia type 1 by blocking an enzyme in the tyrosine breakdown pathway.

Yes, Nitisinone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1337. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 115355. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C14H10F3NO5
Synonymes: 3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.