Orlistat

CHEMBL175247 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

495.7 g/mol

LogP

10.0

Phase

4

A weight-loss medication blocking about one-third of dietary fat absorption in the gut.

Masse moléculaire

495,7000 g/mol

LogP

10,00

TPSA

81,70 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Asthma Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Hyperlipidemia Obesity Type 2 Diabetes Hypertension Gout Hepatitis C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O

InChI

InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1

Molecular Formula

C29H53NO5

HBD / HBA

1 / 5

Liaisons Rotatives

23

Atomes Lourds

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A weight-loss medication blocking about one-third of dietary fat absorption in the gut.

Yes, Orlistat is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL175247. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3034010. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C29H53NO5
Synonymes: 2

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.