Osilodrostat

CHEMBL3099695 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

227.2 g/mol

LogP

1.9

Phase

4

An inhibitor of 11-beta-hydroxylase used to treat Cushing's disease and other forms of hypercortisolism by blocking cortisol synthesis in the adrenal glands. Reducing excess cortisol levels helps reverse the metabolic, cardiovascular, and psychological complications of this condition.

Masse moléculaire

227,2400 g/mol

LogP

1,90

TPSA

41,60 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

N#Cc1ccc([C@H]2CCc3cncn32)c(F)c1

InChI

InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1

Molecular Formula

C13H10FN3

HBD / HBA

- / 3

Liaisons Rotatives

1

Atomes Lourds

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An inhibitor of 11-beta-hydroxylase used to treat Cushing's disease and other forms of hypercortisolism by blocking cortisol synthesis in the adrenal glands. Reducing excess cortisol levels helps reverse the metabolic, cardiovascular, and psychological complications of this condition.

Yes, Osilodrostat is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3099695. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 44139752. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C13H10FN3
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.