Pentostatin
This chemotherapy drug treats hairy cell leukemia by blocking an enzyme leukemia cells need to survive.
Masse moléculaire
268,2700 g/mol
LogP
-2,10
TPSA
112,00 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
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SMILES
OC[C@H]1O[C@@H](n2cnc3c2N=CNC[C@H]3O)C[C@@H]1O
InChI
InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1
Molecular Formula
C11H16N4O4
HBD / HBA
4 / 6
Liaisons Rotatives
2
Atomes Lourds
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
This chemotherapy drug treats hairy cell leukemia by blocking an enzyme leukemia cells need to survive.
Yes, Pentostatin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1580. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 439693. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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