Posaconazole

CHEMBL1397 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

700.8 g/mol

LogP

4.6

Phase

4

A broad-spectrum antifungal medication used to prevent and treat serious fungal infections in people whose immune systems are weakened by illness or medications. It is effective against a wide range of fungi and is used both preventatively in high-risk patients and as treatment for established infections.

Masse moléculaire

700,8000 g/mol

LogP

4,60

TPSA

112,00 Å²

Règle des 5 de Lipinski

Non conforme

Aires thérapeutiques

Oncology Obesity Lymphoma Breast Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(N3CCN(c4ccc(OC[C@@H]5CO[C@@](Cn6cncn6)(c6ccc(F)cc6F)C5)cc4)CC3)cc2)c1=O

InChI

InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

Molecular Formula

C37H42F2N8O4

HBD / HBA

1 / 11

Liaisons Rotatives

12

Atomes Lourds

51

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A broad-spectrum antifungal medication used to prevent and treat serious fungal infections in people whose immune systems are weakened by illness or medications. It is effective against a wide range of fungi and is used both preventatively in high-risk patients and as treatment for established infections.

Yes, Posaconazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1397. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 468595. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C37H42F2N8O4
Synonymes: 3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.