Probenecid

CHEMBL897 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

285.4 g/mol

LogP

3.2

Phase

4

Used to treat gout and gouty arthritis by helping the kidneys remove excess uric acid from the body, thereby reducing the buildup of uric acid crystals in the joints that causes pain and swelling. It is also sometimes used to increase the effectiveness and prolong the action of certain antibiotics.

Masse moléculaire

285,3600 g/mol

LogP

3,20

TPSA

83,10 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Pain Management Epilepsy Chronic Kidney Disease Obesity Type 2 Diabetes Hypertension Gout Chronic Pain Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

SVG PNG

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SMILES

CCCN(CCC)S(=O)(=O)c1ccc(C(=O)O)cc1

InChI

InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)

Molecular Formula

C13H19NO4S

HBD / HBA

1 / 5

Liaisons Rotatives

7

Atomes Lourds

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

Used to treat gout and gouty arthritis by helping the kidneys remove excess uric acid from the body, thereby reducing the buildup of uric acid crystals in the joints that causes pain and swelling. It is also sometimes used to increase the effectiveness and prolong the action of certain antibiotics.

Yes, Probenecid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL897. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4911. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C13H19NO4S
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.