Protokylol

CHEMBL1201273 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

331.4 g/mol

LogP

2.1

Phase

4

Protokylol is a catecholamine-based sympathomimetic bronchodilator that activates beta-2 adrenergic receptors in bronchial smooth muscle, causing relaxation and bronchodilation through adenylyl cyclase activation and increased intracellular cAMP. It was used for the management of bronchospasm in asthma and chronic obstructive pulmonary disease before being superseded by more selective and longer-acting beta-2 agonists.

Masse moléculaire

331,4000 g/mol

LogP

2,10

TPSA

91,20 Å²

Règle des 5 de Lipinski

Conforme

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CC(Cc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(O)c1

InChI

InChI=1S/C18H21NO5/c1-11(6-12-2-5-17-18(7-12)24-10-23-17)19-9-16(22)13-3-4-14(20)15(21)8-13/h2-5,7-8,11,16,19-22H,6,9-10H2,1H3

Molecular Formula

C18H21NO5

HBD / HBA

4 / 6

Liaisons Rotatives

6

Atomes Lourds

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

Protokylol is a catecholamine-based sympathomimetic bronchodilator that activates beta-2 adrenergic receptors in bronchial smooth muscle, causing relaxation and bronchodilation through adenylyl cyclase activation and increased intracellular cAMP. It was used for the management of bronchospasm in asthma and chronic obstructive pulmonary disease before being superseded by more selective and longer-acting beta-2 agonists.

Yes, Protokylol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201273. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4969. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C18H21NO5

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.