Technetium Disofenin

CHEMBL2110575 Phase 4 Approuvé Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
g/mol
LogP
Phase
4

Technetium disofenin (99mTc-DISIDA) is a hepatobiliary radiopharmaceutical that is taken up by hepatocytes via organic anion transport mechanisms and excreted into bile, enabling scintigraphic evaluation of hepatobiliary function and biliary tract patency. It is used in hepatobiliary imaging to assess conditions such as acute cholecystitis, biliary obstruction, and post-operative biliary leaks. The pattern of radiotracer uptake and excretion provides functional information about hepatocyte integrity and biliary flow.

Mécanisme d'action

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

Technetium disofenin (99mTc-DISIDA) is a hepatobiliary radiopharmaceutical that is taken up by hepatocytes via organic anion transport mechanisms and excreted into bile, enabling scintigraphic evaluation of hepatobiliary function and biliary tract patency. It is used in hepatobiliary imaging to assess conditions such as acute cholecystitis, biliary obstruction, and post-operative biliary leaks. The pattern of radiotracer uptake and excretion provides functional information about hepatocyte integrity and biliary flow.

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Yes, Technetium Disofenin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2110575. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.