Technetium Tc 99M Bicisate
Technetium Tc 99m bicisate (99mTc-ECD) is a lipophilic ester that diffuses freely across the blood-brain barrier and is subsequently hydrolyzed intracellularly to a charged form that is retained in brain tissue, enabling SPECT cerebral perfusion imaging. It is used in the evaluation of stroke, epilepsy, dementia, and other cerebrovascular conditions. See technetium-bicisate for additional pharmacological details.
Masse moléculaire
434,3000 g/mol
TPSA
68,60 Ų
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
SMILES
CCOC(=O)[C@H](C[S-])NCC[N-][C@@H](C[S-])C(=O)OCC.[O-2].[Tc]
InChI
InChI=1S/C12H23N2O4S2.O.Tc/c1-3-17-11(15)9(7-19)13-5-6-14-10(8-20)12(16)18-4-2;;/h9-10,13,19-20H,3-8H2,1-2H3;;/q-1;-2;/p-2/t9-,10-;;/m0../s1
Molecular Formula
C12H21N2O5S2Tc-5
HBD / HBA
1 / 9
Liaisons Rotatives
13
Atomes Lourds
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
Technetium Tc 99m bicisate (99mTc-ECD) is a lipophilic ester that diffuses freely across the blood-brain barrier and is subsequently hydrolyzed intracellularly to a charged form that is retained in brain tissue, enabling SPECT cerebral perfusion imaging. It is used in the evaluation of stroke, epilepsy, dementia, and other cerebrovascular conditions. See technetium-bicisate for additional pharmacological details.
Yes, Technetium Tc 99M Bicisate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1237111. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 155491161. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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