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Trazodone Hydrochloride

CHEMBL1200798 Phase 4 Approuvé Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
408.3 g/mol
LogP
—
Phase
4

A hydrochloride salt form of trazodone with the same therapeutic properties. This antidepressant medication is prescribed for depression and is widely used off-label to treat insomnia because of its sedating properties.

Masse moléculaire

408,3000 g/mol

TPSA

42,40 Ų

Aires thérapeutiques

Cardiovascular Disease Psychiatry Respiratory Disease Pain Management Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Schizophrenia Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Hypertension Major Depressive Disorder Chronic Pain

Mécanisme d'action

Serotonin antagonist and reuptake inhibitor (SARI).

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Serotonin antagonist and reuptake inhibitor (SARI).

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cl.O=c1n(CCCN2CCN(c3cccc(Cl)c3)CC2)nc2ccccn12

                

                

                
                

                    
InChI

                    
InChI=1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H23Cl2N5O

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Liaisons Rotatives

                        
5

                    

                    
                    
                    

                        
Atomes Lourds

                        
27

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
A hydrochloride salt form of trazodone with the same therapeutic properties. This antidepressant medication is prescribed for depression and is widely used off-label to treat insomnia because of its sedating properties.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serotonin antagonist and reuptake inhibitor (SARI).

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Trazodone Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200798.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 62935.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.