Vinyl Chloride
Vinyl chloride (chloroethylene) is an industrial chemical and known human carcinogen classified as a Group 1 carcinogen by IARC, primarily associated with hepatic angiosarcoma and other liver cancers upon chronic occupational exposure. It is metabolized to reactive epoxide intermediates that form DNA adducts, causing mutations in oncogenes and tumor suppressor genes. In medical contexts, it is studied as an occupational toxicant and chemical carcinogen model rather than as a therapeutic agent.
Masse moléculaire
62,5000 g/mol
LogP
1,50
TPSA
0,00 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
Embed this structure
SMILES
C=CCl
InChI
InChI=1S/C2H3Cl/c1-2-3/h2H,1H2
Molecular Formula
C2H3Cl
HBD / HBA
- / -
Liaisons Rotatives
0
Atomes Lourds
3
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
Vinyl chloride (chloroethylene) is an industrial chemical and known human carcinogen classified as a Group 1 carcinogen by IARC, primarily associated with hepatic angiosarcoma and other liver cancers upon chronic occupational exposure. It is metabolized to reactive epoxide intermediates that form DNA adducts, causing mutations in oncogenes and tumor suppressor genes. In medical contexts, it is studied as an occupational toxicant and chemical carcinogen model rather than as a therapeutic agent.
Yes, Vinyl Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2311071. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6338. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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