Xenon
Xenon is a noble gas that produces general anesthesia through NMDA receptor antagonism and potassium channel activation, with additional neuroprotective properties attributed to NMDA blockade and HIF-1alpha activation. It is used clinically as an inhalation anesthetic in some European countries, offering advantages including rapid induction and recovery, cardiovascular stability, and absence of hepatotoxicity, and has been investigated for neuroprotection in ischemia-reperfusion injury and asphyxia. As a radioactive isotope (133Xe), it is used in pulmonary ventilation scintigraphy.
Masse moléculaire
131,2900 g/mol
TPSA
0,00 Ų
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
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SMILES
[Xe]
InChI
InChI=1S/Xe
Molecular Formula
Xe
HBD / HBA
- / -
Liaisons Rotatives
0
Atomes Lourds
1
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
Xenon is a noble gas that produces general anesthesia through NMDA receptor antagonism and potassium channel activation, with additional neuroprotective properties attributed to NMDA blockade and HIF-1alpha activation. It is used clinically as an inhalation anesthetic in some European countries, offering advantages including rapid induction and recovery, cardiovascular stability, and absence of hepatotoxicity, and has been investigated for neuroprotection in ischemia-reperfusion injury and asphyxia. As a radioactive isotope (133Xe), it is used in pulmonary ventilation scintigraphy.
Yes, Xenon is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1236802. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23991. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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