Afatinib vs Citalopram

## Afatinib vs Citalopram: Overview

This comparison examines the pharmacological differences between **Afatinib** and **Citalopram**.

## Mechanism of Action

**Afatinib**: Irreversible covalent inhibitor of ErbB family (EGFR/HER1, HER2, HER4) tyrosine kinases.

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

## Pharmacokinetics

**Half-life**: Afatinib — 37 hours; Citalopram — 35 hours.

## Chemical Properties

**Molecular Formula**: Afatinib — C24H25ClFN5O3; Citalopram — C20H21FN2O.

**Molecular Weight**: Afatinib — 485.9400 g/mol; Citalopram — 324.3920 g/mol.

**Type**: Afatinib — Small molecule; Citalopram — Small molecule.